I guess the only down side to always being on reserve is that there's no reserve for reserve. When your out your out.

 

Hey Cody.
It' not bad for the bike. The [ON] setting and the [RES] setting on the petcock are drawing the fuel from the same tank, just at different levels. It's not bad for the bike and the reserve is not a separate tank within the tank.
Peace!
-CCinC